Brief Information of the Compound and Protein
Compound Name
1-[4-[1,4']Bipiperidinyl-1'-yl-2-(3,4-dichloro-phenyl)-butyl]-3-(4-trifluoromethyl-phenyl)-urea
    Show/Hide
PubChem ID
CID: 23567394
Canonical SMILES
FC(F)(F)c1ccc(NC(=O)NCC(CCN2CCC(CC2)N2CCCCC2)c2ccc(Cl)c(Cl)c2)cc1
    Show/Hide
Compound Formula C28H35Cl2F3N4O
Compound Structure
Protein Name
Melanin-concentrating hormone receptor 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
MCH receptor
Uniprot ID
Q99705
Gene Name
MCHR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 1100 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 1080 nM