Brief Information of the Compound and Protein
Compound Name
1-[[2-[4-benzyl-4-(dimethylamino)piperidin-1-yl]-4-(trifluoromethyl)phenyl]methyl]-3-(2,3-dihydro-1-benzofuran-6-yl)urea
    Show/Hide
PubChem ID
CID: 155525842
Canonical SMILES
CN(C)C1(Cc2ccccc2)CCN(CC1)c1cc(ccc1CNC(=O)Nc1ccc2CCOc2c1)C(F)(F)F
    Show/Hide
Compound Formula C31H35F3N4O2
Compound Structure
Protein Name
Transient receptor potential cation channel subfamily V member 1
Protein Classification
Ion channel
>
Voltage-gated ion channel
>
Transient receptor potential channel
Uniprot ID
Q8NER1
Gene Name
TRPV1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
EC50 = 31.3 nM
   TI
   LI
   LO
   TS
2
Ki = 41.4 nM
   TI
   LI
   LO
   TS