Brief Information of the Compound and Protein
Compound Name
1-[[2-[4-benzyl-4-(dimethylamino)piperidin-1-yl]-4-(trifluoromethyl)phenyl]methyl]-3-[3-fluoro-4-(methanesulfonamidomethyl)phenyl]urea
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PubChem ID
CID: 155562884
Canonical SMILES
CN(C)C1(Cc2ccccc2)CCN(CC1)c1cc(ccc1CNC(=O)Nc1ccc(CNS(C)(=O)=O)c(F)c1)C(F)(F)F
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Compound Formula C31H37F4N5O3S
Compound Structure
Protein Name
Transient receptor potential cation channel subfamily V member 1
Protein Classification
Ion channel
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Voltage-gated ion channel
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Transient receptor potential channel
Uniprot ID
Q8NER1
Gene Name
TRPV1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
EC50 = 25 nM
   TI
   LI
   LO
   TS
2
Ki = 16.4 nM
   TI
   LI
   LO
   TS