Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3-b][1,5]benzodiazepine
    Show/Hide
 PubChem ID
CID: 135398745
SID: 14923451
Canonical SMILES
CN1CCN(CC1)C1=Nc2ccccc2Nc2sc(C)cc12
    Show/Hide
Compound Formula C17H20N4S
Compound Structure
Protein Name
 Protein Info 
5-hydroxytryptamine receptor 6
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Serotonin receptor
Uniprot ID
P50406
Gene Name
HTR6
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  5
1
Ki = 5 nM
   TI
   LI
   LO
   TS
2
Ki = 7 nM
   TI
   LI
   LO
   TS
3
Ki = 7.943 nM
   TI
   LI
   LO
   TS
4
Ki = 8.8 nM
   TI
   LI
   LO
   TS
5
Ki = 10.7 nM
   TI
   LI
   LO
   TS
CL000017 HeLa
 Cell Line Info 
Homo sapiens (Human)  1
1
Ki = 6 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 10 nM
2 Ki = 10.7 nM
3 Ki < 50 nM