Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-(3-methylphenyl)-2-[4-(5-methylpyridin-2-yl)piperidin-1-yl]acetamide
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 PubChem ID
CID: 155562395
Canonical SMILES
Cc1ccc(nc1)C1CCN(CC(=O)Nc2cccc(C)c2)CC1
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Compound Formula C20H25N3O
Compound Structure
Protein Name
 Protein Info 
D(4) dopamine receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Dopamine receptor
Uniprot ID
P21917
Gene Name
DRD4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
IC50 = 394 nM
   TI
   LI
   LO
   TS
2
IC50 = 453 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  2
1
Ki = 6.87 nM
   TI
   LI
   LO
   TS
2
Ki = 41.7 nM
   TI
   LI
   LO
   TS