Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-[4-(5-chloropyridin-2-yl)piperazin-1-yl]-N-pyridin-3-ylacetamide
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 PubChem ID
CID: 155568411
Canonical SMILES
Clc1ccc(nc1)N1CCN(CC(=O)Nc2cccnc2)CC1
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Compound Formula C16H18ClN5O
Compound Structure
Protein Name
 Protein Info 
D(4) dopamine receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Dopamine receptor
Uniprot ID
P21917
Gene Name
DRD4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
IC50 = 23450 nM
   TI
   LI
   LO
   TS
2
IC50 = 40000 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
Ki = 5000 nM
   TI
   LI
   LO
   TS