Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-(3-methylphenyl)-3-(4-pyrimidin-2-ylpiperazin-1-yl)propanamide
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 PubChem ID
CID: 109030515
Canonical SMILES
Cc1cccc(NC(=O)CCN2CCN(CC2)c2ncccn2)c1
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Compound Formula C18H23N5O
Compound Structure
Protein Name
 Protein Info 
D(3) dopamine receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Dopamine receptor
Uniprot ID
P35462
Gene Name
DRD3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 > 50000 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  2
1
Ki = 4530 nM
   TI
   LI
   LO
   TS
2
Ki = 9350 nM
   TI
   LI
   LO
   TS