Brief Information of the Compound and Protein
Compound Name
US9180116, 2C
    Show/Hide
PubChem ID
CID: 72722131
Canonical SMILES
CCC#CC[C@H](C)[C@H](O)\C=C\[C@H]1CC(F)(F)C(=O)N1CCCCCCC(O)=O
    Show/Hide
Compound Formula C21H31F2NO4
Compound Structure
Protein Name
Prostaglandin E2 receptor EP4 subtype
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Lipid-like ligand receptor (family A GPCR)
>
Prostanoid receptor
Uniprot ID
P35408
Gene Name
PTGER4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 0.378 nM
   TI
   LI
   LO
   TS
CL000314 HEK293T/17 Homo sapiens (Human)  2
1
EC50 = 0.088 nM
   TI
   LI
   LO
   TS
2
EC50 = 2.631 nM
   TI
   LI
   LO
   TS