Brief Information of the Compound and Protein
Compound Name
4-(2-((1R,2R,3R)-3-hydroxy-2-((S,E)-3-hydroxy-4-(3-(methoxymethyl)phenyl)but-1-enyl)-5-oxocyclopentyl)ethylthio)butanoic acid
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PubChem ID
CID: 9824353
SID: 14783452
Canonical SMILES
COCc1cccc(C[C@H](O)\C=C\[C@H]2[C@H](O)CC(=O)[C@@H]2CCSCCCC(O)=O)c1
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Compound Formula C23H32O6S
Compound Structure
Protein Name
Prostaglandin E2 receptor EP4 subtype
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Lipid-like ligand receptor (family A GPCR)
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Prostanoid receptor
Uniprot ID
P35408
Gene Name
PTGER4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 0.396 nM
   TI
   LI
   LO
   TS
CL000314 HEK293T/17 Homo sapiens (Human)  2
1
EC50 = 0.01 nM
   TI
   LI
   LO
   TS
2
EC50 = 0.142 nM
   TI
   LI
   LO
   TS