Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-fluoro-3-phenyl-2-[(1S)-1-(7H-purin-6-ylamino)propyl]quinazolin-4-one
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 PubChem ID
CID: 11625818
SID: 16728852
Canonical SMILES
CC[C@H](Nc1ncnc2nc[nH]c12)c1nc2cccc(F)c2c(=O)n1-c1ccccc1
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Compound Formula C22H18FN7O
Compound Structure
Protein Name
 Protein Info 
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
Protein Classification
Enzyme
>
Transferase
Uniprot ID
P42338
Gene Name
PIK3CB
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000012 Sf21
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 154 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 120.1 nM
2 IC50 = 129 nM
3 IC50 = 134 nM
4 IC50 = 139.1 nM
5 IC50 = 281 nM
6 IC50 = 380 nM
7 IC50 = 562 nM
8 IC50 = 565 nM
9 IC50 = 571 nM
10 IC50 = 669 nM
11 IC50 = 845.5 nM
12 IC50 = 1400 nM
13 IC50 = 1995.26 nM
14 IC50 = 4000 nM
15 IC50 > 500 nM