Brief Information of the Compound and Protein
Compound Name
methyl (E,5S,6R)-5,6-dihydroxy-8-[5-[(1R)-1-hydroxyhexyl]-2,3-diphenylimidazol-4-yl]oct-7-enoate
    Show/Hide
PubChem ID
CID: 153047598
Canonical SMILES
CCCCC[C@@H](O)c1nc(-c2ccccc2)n(c1\C=C\[C@@H](O)[C@@H](O)CCCC(=O)OC)-c1ccccc1
    Show/Hide
Compound Formula C30H38N2O5
Compound Structure
Protein Name
N-formyl peptide receptor 2
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
N-formyl methionyl peptide receptor
Uniprot ID
P25090
Gene Name
FPR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000040 THP-1 Homo sapiens (Human)  6
1
IC50 = 0.5 nM
   TI
   LI
   LO
   TS
2
IC50 = 1.4 nM
   TI
   LI
   LO
   TS
3
IC50 = 7.1 nM
   TI
   LI
   LO
   TS
4
IC50 = 10 nM
   TI
   LI
   LO
   TS
5
IC50 = 18.5 nM
   TI
   LI
   LO
   TS
6
IC50 = 26.2 nM
   TI
   LI
   LO
   TS