Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-[4-(difluoromethoxy)-6-[4-[2-[1-hydroxy-3-[4-[(1R,2S)-6-hydroxy-2-phenyl-1,2,3,4-tetrahydronaphthalen-1-yl]phenoxy]cyclobutyl]ethyl]piperazin-1-yl]-3-oxo-1H-isoindol-2-yl]piperidine-2,6-dione
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 PubChem ID
CID: 146567377
Canonical SMILES
Oc1ccc2[C@H]([C@H](CCc2c1)c1ccccc1)c1ccc(OC2CC(O)(CCN3CCN(CC3)c3cc4CN(C5CCC(=O)NC5=O)C(=O)c4c(OC(F)F)c3)C2)cc1
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Compound Formula C46H48F2N4O7
Compound Structure
Protein Name
 Protein Info 
Estrogen receptor
Protein Classification
Transcription factor
>
Nuclear receptor
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Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group A
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Nuclear hormone receptor subfamily 3 group A member 1
Uniprot ID
P03372
Gene Name
ESR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000078 T-47D
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 0.5 nM
   TI
   LI
   LO
   TS