Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-[4-[[2-[[6-[5-chloro-6-(dimethylamino)pyrimidin-4-yl]-1H-benzimidazol-2-yl]amino]pyridin-4-yl]methyl]piperazin-1-yl]-3,3,3-trifluoropropan-1-one
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 PubChem ID
CID: 137479135
Canonical SMILES
CN(C)c1ncnc(-c2ccc3nc(Nc4cc(CN5CCN(CC5)C(=O)CC(F)(F)F)ccn4)[nH]c3c2)c1Cl
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Compound Formula C26H27ClF3N9O
Compound Structure
Protein Name
 Protein Info 
Receptor-type tyrosine-protein kinase FLT3
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase PDGFR family
Uniprot ID
P36888
Gene Name
FLT3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000012 Sf21
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 536 nM
   TI
   LI
   LO
   TS