Brief Information of the Compound and Protein
Compound Name
4-tert-butyl-N-[4-(hydroxycarbamoyl)phenyl]benzamide
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PubChem ID
CID: 11688197
SID: 16792515
Canonical SMILES
CC(C)(C)c1ccc(cc1)C(=O)Nc1ccc(cc1)C(=O)NO
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Compound Formula C18H20N2O3
Compound Structure
Protein Name
Histone deacetylase 6
Protein Classification
Epigenetic regulator
>
Eraser
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Histone deacetylase
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HDAC class IIb
Uniprot ID
Q9UBN7
Gene Name
HDAC6
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000017 HeLa Homo sapiens (Human)  1
1
IC50 = 580 nM
   TI
   LI
   LO
   TS
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  2
1
IC50 = 24.4 nM
   TI
   LI
   LO
   TS
2
Ki = 35 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 24 nM