Brief Information of the Compound and Protein
Compound Name
 Compound Info 
JNJ-26481585
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 PubChem ID
CID: 11538455
SID: 16640562
Canonical SMILES
Cn1cc(CNCC2CCN(CC2)c2ncc(cn2)C(=O)NO)c2ccccc12
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Compound Formula C21H26N6O2
Compound Structure
Protein Name
 Protein Info 
Polyamine deacetylase HDAC10
Protein Classification
Epigenetic regulator
>
Eraser
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Histone deacetylase
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HDAC class IIb
Uniprot ID
Q969S8
Gene Name
HDAC10
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000017 HeLa
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 39.81 nM
   TI
   LI
   LO
   TS
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 1.96 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.46 nM
2 IC50 = 0.5 nM
3 IC50 = 2.8 nM
4 IC50 = 10 nM
5 Ki = 0.05 nM
6 Ki = 4.4 nM