Brief Information of the Compound and Protein
Compound Name
JNJ-26481585
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PubChem ID
CID: 11538455
SID: 16640562
Canonical SMILES
Cn1cc(CNCC2CCN(CC2)c2ncc(cn2)C(=O)NO)c2ccccc12
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Compound Formula C21H26N6O2
Compound Structure
Protein Name
Histone deacetylase 4
Protein Classification
Epigenetic regulator
>
Eraser
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Histone deacetylase
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HDAC class IIa
Uniprot ID
P56524
Gene Name
HDAC4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 4.61 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.64 nM
2 Ki = 0.3 nM
3 Ki = 6.7 nM