Brief Information of the Compound and Protein
Compound Name
(4-(((6-amino-5-(4-phenoxyphenyl)pyrimidin-4-yl)amino)methyl)piperidin-1-yl)(cyclobut-1-en-1-yl)methanone
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PubChem ID
CID: 71474333
SID: 163442601
Canonical SMILES
Nc1ncnc(NCC2CCN(CC2)C(=O)C2=CCC2)c1-c1ccc(Oc2ccccc2)cc1
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Compound Formula C27H29N5O2
Compound Structure
Protein Name
Tyrosine-protein kinase BTK
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase Tec family
Uniprot ID
Q06187
Gene Name
BTK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000752 PBMC iPSC #1 Homo sapiens (Human)  1
1
IC50 = 290 nM
   TI
   LI
   LO
   TS