Brief Information of the Compound and Protein
Compound Name
2-methoxy-6,7-dimethyl-9-propylimidazo[1,5-a]pyrido[3,2-e]pyrazine
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PubChem ID
CID: 24802717
SID: 49748846
Canonical SMILES
CCCc1nc(C)c2c(C)nc3ccc(OC)nc3n12
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Compound Formula C15H18N4O
Compound Structure
Protein Name
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
Protein Classification
Enzyme
>
Phosphodiesterase
>
Phosphodiesterase 10
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Phosphodiesterase 10A
Uniprot ID
Q9Y233
Gene Name
PDE10A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 17 nM
   TI
   LI
   LO
   TS
CL000012 Sf21 Spodoptera frugiperda (Fall armyworm)  2
1
IC50 = 7 nM
   TI
   LI
   LO
   TS
2
IC50 = 7.28 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 32 nM