Brief Information of the Compound and Protein
Compound Name
N-[4-(3-chloro-4-fluoroanilino)-7-[[1-[(4-methylphenyl)methyl]triazol-4-yl]methoxy]quinazolin-6-yl]prop-2-enamide
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PubChem ID
CID: 155559257
Canonical SMILES
Cc1ccc(Cn2cc(COc3cc4ncnc(Nc5ccc(F)c(Cl)c5)c4cc3NC(=O)C=C)nn2)cc1
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Compound Formula C28H23ClFN7O2
Compound Structure
Protein Name
Epidermal growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000012 Sf21 Spodoptera frugiperda (Fall armyworm)  2
1
IC50 = 15 nM
   TI
   LI
   LO
   TS
2
IC50 = 105 nM
   TI
   LI
   LO
   TS