Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-(4-cyclobutyl-1,4-diazepan-1-yl)-N-[4-(1-cyclobutylpiperidin-4-yl)oxy-2-(trifluoromethyl)phenyl]acetamide
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 PubChem ID
CID: 155524804
Canonical SMILES
FC(F)(F)c1cc(OC2CCN(CC2)C2CCC2)ccc1NC(=O)CN1CCCN(CC1)C1CCC1
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Compound Formula C27H39F3N4O2
Compound Structure
Protein Name
 Protein Info 
Histamine H3 receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Histamine receptor
Uniprot ID
Q9Y5N1
Gene Name
HRH3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki = 1.61 nM
   TI
   LI
   LO
   TS