Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-[(1S,2R,3S,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-2-bicyclo[3.1.0]hexanyl]-1,2,4-triazole-3-carboxamide
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 PubChem ID
CID: 155536619
Canonical SMILES
NC(=O)c1ncn(n1)[C@@H]1[C@H]2C[C@@]2(CO)[C@@H](O)[C@H]1O
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Compound Formula C10H14N4O4
Compound Structure
Protein Name
 Protein Info 
Adenosine receptor A1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Nucleotide-like receptor (family A GPCR)
>
Adenosine receptor
Uniprot ID
P30542
Gene Name
ADORA1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki = 495 nM
   TI
   LI
   LO
   TS
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
EC50 = 2460 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  2
1
EC50 = 758 nM
   TI
   LI
   LO
   TS
2
IC50 = 87 nM
   TI
   LI
   LO
   TS