Brief Information of the Compound and Protein
Compound Name
2-((5-Chlorothiophen-2-yl)ethynyl)-N-cyclopentyl-9H-purin-6-amine
    Show/Hide
PubChem ID
CID: 144852560
Canonical SMILES
Clc1ccc(C#Cc2nc(NC3CCCC3)c3nc[nH]c3n2)s1
    Show/Hide
Compound Formula C16H14ClN5S
Compound Structure
Protein Name
Adenosine receptor A3
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Nucleotide-like receptor (family A GPCR)
>
Adenosine receptor
Uniprot ID
P0DMS8
Gene Name
ADORA3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
EC50 = 276 nM
   TI
   LI
   LO
   TS
2
Ki = 17.4 nM
   TI
   LI
   LO
   TS