Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-[5-chloro-3-(5-methoxy-3,4-dihydro-1H-isoquinoline-2-carbonyl)-2-methylindol-1-yl]-N-(1-prop-2-enoylazetidin-3-yl)acetamide
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 PubChem ID
CID: 146630894
Canonical SMILES
COc1cccc2CN(CCc12)C(=O)c1c(C)n(CC(=O)NC2CN(C2)C(=O)C=C)c2ccc(Cl)cc12
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Compound Formula C28H29ClN4O4
Compound Structure
Protein Name
 Protein Info 
GTPase KRas
Protein Classification
Enzyme
>
Hydrolase
Uniprot ID
P01116
Gene Name
KRAS
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000207 MIA PaCa-2
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 3550 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 369 nM