Brief Information of the Compound and Protein
Compound Name
 Compound Info 
BMS-777607
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 PubChem ID
CID: 24794418
SID: 49738159
Canonical SMILES
CCOc1ccn(-c2ccc(F)cc2)c(=O)c1C(=O)Nc1ccc(Oc2ccnc(N)c2Cl)c(F)c1
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Compound Formula C25H19ClF2N4O4
Compound Structure
Protein Name
 Protein Info 
Hepatocyte growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Met family
Uniprot ID
P08581
Gene Name
MET
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000413 MKN45
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 46.6 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 2.6 nM
2 IC50 = 3.7 nM
3 IC50 = 3.9 nM
4 IC50 = 7 nM
5 IC50 = 7.6 nM
6 IC50 = 12 nM