Brief Information of the Compound and Protein
Compound Name
2-[(5-cyclopropyl-1H-1,2,4-triazol-3-yl)sulfanyl]-N-[2-phenyl-5-(2,4,5-trimethylphenyl)pyrazol-3-yl]acetamide
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PubChem ID
CID: 17555821
Canonical SMILES
Cc1cc(C)c(cc1C)-c1cc(NC(=O)CSc2n[nH]c(n2)C2CC2)n(n1)-c1ccccc1
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Compound Formula C25H26N6OS
Compound Structure
Protein Name
ATP-dependent translocase ABCB1
Protein Classification
Transporter
>
Primary active transporter
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ATP-binding cassette
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ABCB subfamily
Uniprot ID
P08183
Gene Name
ABCB1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000946 DU145-TxR Homo sapiens (Human)  4
1
IC50 = 59 nM
   TI
   LI
   LO
   TS
2
IC50 = 101 nM
   TI
   LI
   LO
   TS
3
IC50 = 194 nM
   TI
   LI
   LO
   TS
4
IC50 = 629 nM
   TI
   LI
   LO
   TS