Brief Information of the Compound and Protein
Compound Name
N-[2-phenyl-5-(2,4,5-trimethylphenyl)pyrazol-3-yl]-2-(5H-[1,2,4]triazino[5,6-b]indol-3-ylsulfanyl)acetamide
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PubChem ID
CID: 146430218
Canonical SMILES
Cc1cc(C)c(cc1C)-c1cc(NC(=O)CSc2nnc3c(n2)[nH]c2ccccc32)n(n1)-c1ccccc1
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Compound Formula C29H25N7OS
Compound Structure
Protein Name
ATP-dependent translocase ABCB1
Protein Classification
Transporter
>
Primary active transporter
>
ATP-binding cassette
>
ABCB subfamily
Uniprot ID
P08183
Gene Name
ABCB1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000946 DU145-TxR Homo sapiens (Human)  3
1
IC50 = 17 nM
   TI
   LI
   LO
   TS
2
IC50 = 21 nM
   TI
   LI
   LO
   TS
3
IC50 = 426 nM
   TI
   LI
   LO
   TS