Brief Information of the Compound and Protein
Compound Name
N-(1,3-benzothiazol-6-yl)-2-[2-oxo-2-[[2-phenyl-5-(2,4,5-trimethylphenyl)pyrazol-3-yl]amino]ethyl]sulfanylacetamide
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PubChem ID
CID: 135185934
Canonical SMILES
Cc1cc(C)c(cc1C)-c1cc(NC(=O)CSCC(=O)Nc2ccc3ncsc3c2)n(n1)-c1ccccc1
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Compound Formula C29H27N5O2S2
Compound Structure
Protein Name
ATP-dependent translocase ABCB1
Protein Classification
Transporter
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Primary active transporter
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ATP-binding cassette
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ABCB subfamily
Uniprot ID
P08183
Gene Name
ABCB1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000946 DU145-TxR Homo sapiens (Human)  4
1
IC50 = 0.78 nM
   TI
   LI
   LO
   TS
2
IC50 = 2.9 nM
   TI
   LI
   LO
   TS
3
IC50 = 34 nM
   TI
   LI
   LO
   TS
4
IC50 = 172 nM
   TI
   LI
   LO
   TS