Brief Information of the Compound and Protein
Compound Name
2-[2-oxo-2-[[2-phenyl-5-(2,4,5-trimethylphenyl)pyrazol-3-yl]amino]ethyl]sulfanyl-N-(3,4,5-trimethoxyphenyl)acetamide
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PubChem ID
CID: 135185944
Canonical SMILES
COc1cc(NC(=O)CSCC(=O)Nc2cc(nn2-c2ccccc2)-c2cc(C)c(C)cc2C)cc(OC)c1OC
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Compound Formula C31H34N4O5S
Compound Structure
Protein Name
ATP-dependent translocase ABCB1
Protein Classification
Transporter
>
Primary active transporter
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ATP-binding cassette
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ABCB subfamily
Uniprot ID
P08183
Gene Name
ABCB1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000946 DU145-TxR Homo sapiens (Human)  4
1
IC50 = 0.07 nM
   TI
   LI
   LO
   TS
2
IC50 = 0.64 nM
   TI
   LI
   LO
   TS
3
IC50 = 1.9 nM
   TI
   LI
   LO
   TS
4
IC50 = 185 nM
   TI
   LI
   LO
   TS