Brief Information of the Compound and Protein
Compound Name
8-fluoro-2-(4-methylpiperazin-1-yl)indolo[2,1-b]quinazoline-6,12-dione
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PubChem ID
CID: 85469240
Canonical SMILES
CN1CCN(CC1)c1ccc2nc3C(=O)c4cc(F)ccc4-n3c(=O)c2c1
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Compound Formula C20H17FN4O2
Compound Structure
Protein Name
Indoleamine 2,3-dioxygenase 2
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
Q6ZQW0
Gene Name
IDO2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000102 U-87MG ATCC Homo sapiens (Human)  1
1
IC50 = 79000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 18440 nM