Brief Information of the Compound and Protein
Compound Name
(1S,3R,4R,6R)-N-[1-methyl-5-(trifluoromethyl)pyrazol-4-yl]-4-[4-(1H-pyrazol-5-yl)benzoyl]bicyclo[4.1.0]heptane-3-carboxamide
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PubChem ID
CID: 155544322
Canonical SMILES
Cn1ncc(NC(=O)[C@@H]2C[C@@H]3C[C@@H]3C[C@H]2C(=O)c2ccc(cc2)-c2cc[nH]n2)c1C(F)(F)F
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Compound Formula C23H22F3N5O2
Compound Structure
Protein Name
Arachidonate 5-lipoxygenase-activating protein
Protein Classification
Other cytosolic protein
Uniprot ID
P20292
Gene Name
ALOX5AP
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000053 COS-7 Chlorocebus aethiops (Green monkey)  1
1
IC50 = 12.59 nM
   TI
   LI
   LO
   TS