Brief Information of the Compound and Protein
Compound Name
(9-Carbamoyl-4-{4-[2-(3,4-difluoro-phenyl)-ethyl]-piperazin-1-yl}-pyrimido[5,4-b]indol-5-yl)-acetic acid ethyl ester
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PubChem ID
CID: 11477947
SID: 16578739
Canonical SMILES
CCOC(=O)Cn1c2cccc(C(N)=O)c2c2ncnc(N3CCN(CCc4ccc(F)c(F)c4)CC3)c12
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Compound Formula C27H28F2N6O3
Compound Structure
Protein Name
Multidrug resistance-associated protein 1
Protein Classification
Transporter
>
Primary active transporter
>
ATP-binding cassette
>
ABCC subfamily
Uniprot ID
P33527
Gene Name
ABCC1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000712 COR-L23/R Homo sapiens (Human)  1
1
IC50 = 122 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 < 250 nM