Brief Information of the Compound and Protein
Compound Name
6-[4-[(2-chlorophenyl)methyl]piperazin-1-yl]-11,13-dimethyl-8-thia-3,5,10-triazatricyclo[7.4.0.02,7]trideca-1(9),2(7),3,5,10,12-hexaene
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PubChem ID
CID: 17585222
Canonical SMILES
Cc1cc(C)c2c(n1)sc1c(ncnc21)N1CCN(Cc2ccccc2Cl)CC1
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Compound Formula C22H22ClN5S
Compound Structure
Protein Name
Broad substrate specificity ATP-binding cassette transporter ABCG2
Protein Classification
Transporter
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Primary active transporter
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ATP-binding cassette
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ABCG subfamily
Uniprot ID
Q9UNQ0
Gene Name
ABCG2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000036 MDCK-II Canis lupus familiaris (Dog)  1
1
IC50 = 8680 nM
   TI
   LI
   LO
   TS