Brief Information of the Compound and Protein
Compound Name
2-[[3-(1,3-benzodioxol-5-yl)pyrazolo[1,5-a]pyrimidin-5-yl]amino]ethanol
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PubChem ID
CID: 24866217
SID: 50098952
Canonical SMILES
OCCNc1ccn2ncc(-c3ccc4OCOc4c3)c2n1
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Compound Formula C15H14N4O3
Compound Structure
Protein Name
Proto-oncogene tyrosine-protein kinase receptor Ret
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Ret family
Uniprot ID
P07949
Gene Name
RET
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  1
1
IC50 = 6800 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 130 nM