Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(S)-2-{(R)-2-[(S)-2-Acetylamino-3-(1H-imidazol-4-yl)-propionylamino]-3-phenyl-propionylamino}-5-guanidino-pentanoic acid [(S)-1-carbamoyl-2-(1H-indol-3-yl)-ethyl]-amide
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 PubChem ID
CID: 11093672
SID: 57254734
Canonical SMILES
CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O
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Compound Formula C34H43N11O5
Compound Structure
Protein Name
 Protein Info 
Melanocyte-stimulating hormone receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
Melanocortin receptor
Uniprot ID
Q01727
Gene Name
MC1R
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  9
1
EC50 = 13.4 nM
   TI
   LI
   LO
   TS
2
EC50 = 14.1 nM
   TI
   LI
   LO
   TS
3
EC50 = 16 nM
   TI
   LI
   LO
   TS
4
EC50 = 18 nM
   TI
   LI
   LO
   TS
5
EC50 = 20 nM
   TI
   LI
   LO
   TS
6
EC50 = 71 nM
   TI
   LI
   LO
   TS
7
EC50 = 112 nM
   TI
   LI
   LO
   TS
8
EC50 = 140 nM
   TI
   LI
   LO
   TS
9
IC50 = 388 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 20.1 nM