Brief Information of the Compound and Protein
Compound Name
1-[3,5-dimethyl-4-[2-[[4-oxo-2-[4-(trifluoromethoxy)phenyl]-1,3,8-triazaspiro[4.5]dec-1-en-8-yl]sulfonyl]ethyl]phenyl]-3,5,5-trimethylimidazolidine-2,4-dione
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PubChem ID
CID: 155542161
Canonical SMILES
CN1C(=O)N(c2cc(C)c(CCS(=O)(=O)N3CCC4(CC3)N=C(NC4=O)c3ccc(OC(F)(F)F)cc3)c(C)c2)C(C)(C)C1=O
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Compound Formula C30H34F3N5O6S
Compound Structure
Protein Name
Parathyroid hormone/parathyroid hormone-related peptide receptor
Protein Classification
Membrane receptor
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Family B G protein-coupled receptor
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Peptide receptor (family B GPCR)
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Parathyroid hormone receptor
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Parathyroid hormone receptor
Uniprot ID
Q03431
Gene Name
PTH1R
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000009 LLC-PK1 Sus scrofa (Pig)  1
1
EC50 = 5300 nM
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