Brief Information of the Compound and Protein
Compound Name
 Compound Info 
6-(octylamino)-1H-pyrimidine-2,4-dione
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 PubChem ID
CID: 10354234
SID: 15366587
Canonical SMILES
CCCCCCCCNc1cc(=O)[nH]c(=O)[nH]1
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Compound Formula C12H21N3O2
Compound Structure
Protein Name
 Protein Info 
G-protein coupled receptor 84
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
Uniprot ID
Q9NQS5
Gene Name
GPR84
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  3
1
EC50 = 16.7 nM
   TI
   LI
   LO
   TS
2
EC50 = 114 nM
   TI
   LI
   LO
   TS
3
Ki = 0.626 nM
   TI
   LI
   LO
   TS
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
EC50 = 19 nM
   TI
   LI
   LO
   TS
2
EC50 = 11000 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  6
1
EC50 = 105 nM
   TI
   LI
   LO
   TS
2
EC50 = 341 nM
   TI
   LI
   LO
   TS
3
EC50 = 438 nM
   TI
   LI
   LO
   TS
4
EC50 = 653 nM
   TI
   LI
   LO
   TS
5
EC50 = 1250 nM
   TI
   LI
   LO
   TS
6
EC50 = 1750 nM
   TI
   LI
   LO
   TS
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
EC50 = 512 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 512 nM