Brief Information of the Compound and Protein
Compound Name
3-[(5,7-difluoro-1H-indol-3-yl)methyl]-5,7-difluoro-1H-indole
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PubChem ID
CID: 137643701
Canonical SMILES
Fc1cc(F)c2[nH]cc(Cc3c[nH]c4c(F)cc(F)cc34)c2c1
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Compound Formula C17H10F4N2
Compound Structure
Protein Name
G-protein coupled receptor 84
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
Uniprot ID
Q9NQS5
Gene Name
GPR84
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  7
1
EC50 = 41.3 nM
   TI
   LI
   LO
   TS
2
EC50 = 41.5 nM
   TI
   LI
   LO
   TS
3
EC50 = 2680 nM
   TI
   LI
   LO
   TS
4
EC50 = 3580 nM
   TI
   LI
   LO
   TS
5
EC50 = 5470 nM
   TI
   LI
   LO
   TS
6
EC50 = 6520 nM
   TI
   LI
   LO
   TS
7
EC50 = 11400 nM
   TI
   LI
   LO
   TS