Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[5-[6-(4-deuteriotetrahydropyran-4-yl)oxy-5-morpholino-3-pyridyl]-6-methyl-3-pyridyl]-3-(trifluoromethyl)benzamide
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 PubChem ID
CID: 118870913
Canonical SMILES
[2H]C1(Oc2ncc(-c3cc(NC(=O)c4cccc(C(F)(F)F)c4)cnc3C)cc2N2CCOCC2)CCOCC1
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Compound Formula C28H29F3N4O4
Compound Structure
Protein Name
 Protein Info 
RAF proto-oncogene serine/threonine-protein kinase
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase RAF family
Uniprot ID
P04049
Gene Name
RAF1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000187 Calu-6
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 6 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.4 nM