Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US10245267, Example 636
    Show/Hide
 PubChem ID
CID: 90456597
Canonical SMILES
Cc1ncc(NC(=O)c2cccc(c2)C(F)(F)F)cc1-c1cc(N2CCOCC2)c(OC2CCOCC2)nn1
    Show/Hide
Compound Formula C27H28F3N5O4
Compound Structure
Protein Name
 Protein Info 
RAF proto-oncogene serine/threonine-protein kinase
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase RAF family
Uniprot ID
P04049
Gene Name
RAF1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000187 Calu-6
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 8 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.4 nM