Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-[(1S)-1-[6-methyl-1-(2-methylpropyl)benzimidazol-2-yl]-2-[1-(2-methylpropanoyl)piperidin-4-yl]ethyl]-1-(4-phenoxyphenyl)imidazolidine-2,4-dione
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 PubChem ID
CID: 155541843
Canonical SMILES
CC(C)Cn1c(nc2ccc(C)cc12)[C@H](CC1CCN(CC1)C(=O)C(C)C)N1C(=O)CN(C1=O)c1ccc(Oc2ccccc2)cc1
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Compound Formula C38H45N5O4
Compound Structure
Protein Name
 Protein Info 
Bile acid receptor
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 1
>
Nuclear hormone receptor subfamily 1 group H
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Nuclear hormone receptor subfamily 1 group H member 4
Uniprot ID
Q96RI1
Gene Name
NR1H4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000148 Huh-7
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 2.4 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 330 nM