Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-fluoro-N-[(4-fluoropiperidin-4-yl)methyl]-2-(10-methyl-13-oxa-3,4,6,7,10-pentazatricyclo[7.4.0.02,6]trideca-1(9),2,4,7-tetraen-5-yl)quinolin-8-amine
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 PubChem ID
CID: 124005596
Canonical SMILES
CN1CCOc2c1cnn1c(nnc21)-c1ccc2c(F)ccc(NCC3(F)CCNCC3)c2n1
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Compound Formula C23H24F2N8O
Compound Structure
Protein Name
 Protein Info 
Serine/threonine-protein kinase pim-1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
CAMK protein kinase group
>
CAMK protein kinase PIM family
Uniprot ID
P11309
Gene Name
PIM1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000095 NCI-H1299
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 283 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 30 nM