Brief Information of the Compound and Protein
Compound Name
2-(10-methyl-13-oxa-3,4,6,7,10-pentazatricyclo[7.4.0.02,6]trideca-1(9),2,4,7-tetraen-5-yl)-N-[(1-methylpiperidin-4-yl)methyl]quinolin-8-amine
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PubChem ID
CID: 155510554
Canonical SMILES
CN1CCC(CNc2cccc3ccc(nc23)-c2nnc3c4OCCN(C)c4cnn23)CC1
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Compound Formula C24H28N8O
Compound Structure
Protein Name
Serine/threonine-protein kinase pim-1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
CAMK protein kinase group
>
CAMK protein kinase PIM family
Uniprot ID
P11309
Gene Name
PIM1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000095 NCI-H1299 Homo sapiens (Human)  1
1
EC50 = 179 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 14 nM