Brief Information of the Compound and Protein
Compound Name
1-((1S,3R)-5-(1-cyclopropyl- 1H-pyrazol-4-yl)-3- (hydroxymethyl)-1-methyl- 3,4-dihydroisoquinolin-2(1H)- yl)-2-(2,6- dichlorophenyl)ethan-1-one
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PubChem ID
CID: 146192964
Canonical SMILES
C[C@@H]1N([C@@H](CO)Cc2c1cccc2-c1cnn(c1)C1CC1)C(=O)Cc1c(Cl)cccc1Cl
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Compound Formula C25H25Cl2N3O2
Compound Structure
Protein Name
D(1A) dopamine receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
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Monoamine receptor
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Dopamine receptor
Uniprot ID
P21728
Gene Name
DRD1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
EC50 = 10.3 nM
   TI
   LI
   LO
   TS
2
EC50 = 287 nM
   TI
   LI
   LO
   TS