Brief Information of the Compound and Protein
Compound Name
2-(2,6-dichlorophenyl)-1- ((1S,3R)-5-(1-ethyl-1H- pyrazol-4-yl)-3- (hydroxymethyl)-1-methyl- 3,4-dihydroisoquinolin-2(1H)- yl)ethan-1-one
    Show/Hide
PubChem ID
CID: 146192966
Canonical SMILES
CCn1cc(cn1)-c1cccc2[C@H](C)N([C@@H](CO)Cc12)C(=O)Cc1c(Cl)cccc1Cl
    Show/Hide
Compound Formula C24H25Cl2N3O2
Compound Structure
Protein Name
D(1A) dopamine receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Dopamine receptor
Uniprot ID
P21728
Gene Name
DRD1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
EC50 = 15.9 nM
   TI
   LI
   LO
   TS
2
EC50 = 172 nM
   TI
   LI
   LO
   TS