Brief Information of the Compound and Protein
Compound Name
(3S,8S,9S)-8,9,16-trihydroxy-14-methoxy-3-methyl-3,4,9,10,11,12-hexahydro-1H-benzo[c][1]oxacyclotetradecine-1,7(8H)-dione
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PubChem ID
CID: 10498988
SID: 56361061
Canonical SMILES
COc1cc(O)c2c(c1)CCC[C@H](O)[C@H](O)C(=O)/C=C\C[C@H](C)OC2=O
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Compound Formula C19H24O7
Compound Structure
Protein Name
Receptor-type tyrosine-protein kinase FLT3
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase PDGFR family
Uniprot ID
P36888
Gene Name
FLT3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  1
1
GI50 = 270 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1.59 nM
2 IC50 = 1.8 nM
3 IC50 = 11 nM
4 IC50 = 36 nM
5 IC50 = 62 nM