Brief Information of the Compound and Protein
Compound Name
N-[5-[[2-(2,5-dimethylpyridin-4-yl)-2,7-diazaspiro[4.4]nonan-7-yl]methyl]-1,3-thiazol-2-yl]acetamide
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PubChem ID
CID: 135301817
Canonical SMILES
CC(=O)Nc1ncc(CN2CCC3(CCN(C3)c3cc(C)ncc3C)C2)s1
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Compound Formula C20H27N5OS
Compound Structure
Protein Name
Protein O-GlcNAcase
Protein Classification
Enzyme
Uniprot ID
O60502
Gene Name
OGA
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 77.62 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 13.49 nM