Brief Information of the Compound and Protein
Compound Name
N-(3,3-dimethyl-2-oxaspiro[4.5]decan-8-yl)-N-methyl-6-(5-methylsulfonyl-2,3-dihydroindol-1-yl)pyrimidin-4-amine
    Show/Hide
Canonical SMILES
CN([C@H]1CC[C@@]2(COC(C)(C)C2)CC1)c1cc(ncn1)N1CCc2cc(ccc12)S(C)(=O)=O
    Show/Hide
Compound Formula C25H34N4O3S
Compound Structure
Protein Name
Glucose-dependent insulinotropic receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Lipid-like ligand receptor (family A GPCR)
Uniprot ID
Q8TDV5
Gene Name
GPR119
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
EC50 = 16 nM
   TI
   LI
   LO
   TS