Brief Information of the Compound and Protein
Compound Name
4-N-(3,3-dimethyl-2-oxaspiro[4.5]decan-8-yl)-6-N-(2-fluoro-4-methylsulfonylphenyl)pyrimidine-4,6-diamine
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Canonical SMILES
CC1(C)C[C@@]2(CO1)CC[C@@H](CC2)Nc1cc(Nc2ccc(cc2F)S(C)(=O)=O)ncn1
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Compound Formula C22H29FN4O3S
Compound Structure
Protein Name
Glucose-dependent insulinotropic receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Lipid-like ligand receptor (family A GPCR)
Uniprot ID
Q8TDV5
Gene Name
GPR119
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
EC50 = 19 nM
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