Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-[[2,4-dioxo-3-(2-phenylethyl)quinazolin-1-yl]methyl]-N-hydroxybenzamide
    Show/Hide
 PubChem ID
CID: 138377601
Canonical SMILES
ONC(=O)c1ccc(Cn2c3ccccc3c(=O)n(CCc3ccccc3)c2=O)cc1
    Show/Hide
Compound Formula C24H21N3O4
Compound Structure
Protein Name
 Protein Info 
Histone deacetylase 6
Protein Classification
Epigenetic regulator
>
Eraser
>
Histone deacetylase
>
HDAC class IIb
Uniprot ID
Q9UBN7
Gene Name
HDAC6
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  3
1
IC50 = 4 nM
   TI
   LI
   LO
   TS
2
Ki = 1.6 nM
   TI
   LI
   LO
   TS
3
Km = 16700 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 4.7 nM