Brief Information of the Compound and Protein
Compound Name
1-[4-[2-[3-(dimethylamino)propoxy]-7-(3-hydroxynaphthalen-1-yl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-yl]piperazin-1-yl]prop-2-en-1-one
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PubChem ID
CID: 132163177
Canonical SMILES
CN(C)CCCOc1nc2CN(CCc2c(n1)N1CCN(CC1)C(=O)C=C)c1cc(O)cc2ccccc12
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Compound Formula C29H36N6O3
Compound Structure
Protein Name
GTPase KRas
Protein Classification
Enzyme
>
Hydrolase
Uniprot ID
P01116
Gene Name
KRAS
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000268 NCI-H358 Homo sapiens (Human)  1
1
IC50 = 1500 nM
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